The histologic findings in 17 corneal buttons from patients with keratoconus are described. Amyloid deposits were found in three specimens. Five others demonstrated a marked increase in normal corneal birefringence. Iron deposits in corneal epithelium were present in 14 of 16 corneas examined despite the fact that Fleischer's line was noted in only one.
McPherson SD, Kiffney GT. Some Histologic Findings in Keratoconus. Arch Ophthalmol. 1968;79(6):669-673. doi:10.1001/archopht.1968.03850040671004