Fluorescein photography has been performed on two patients with typical intact vitelliform macular lesions, and on an affected sibling of one of these patients who presumably has a later stage of the disorder. The patients with typical intact lesions showed normal fluorescein patterns, and the patient with an ophthalmoscopic appearance of retinal pigment disturbance demonstrated a fluorescein pattern indicating a defect in the retinal pigment epithelium. The significance of this observation in relation to the presumed site of the initial vitelliform abnormality is discussed.
Curry HF, Moorman LT. Fluorescein Photography of Vitelliform Macular Degeneration. Arch Ophthalmol. 1968;79(6):705-709. doi:10.1001/archopht.1968.03850040707008