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Article
June 1968

ALCOHOL IN CRYOSURGERY

Arch Ophthalmol. 1968;79(6):803-804. doi:10.1001/archopht.1968.03850040805031

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Abstract

To the Editor.  —It was of considerable interest to read the letter of L. Christensen, MD, in the March 1968 issue of the Archives (79:359-360 [March] 1968) on the use of liquid silicone for the prevention of cryoprobe adhesion, making the use of a heating element unnecessary. It is always gratifying to find that others have followed the same steps of logic in their reasoning.About a year ago the concept occurred to me that cryoprobe adhesion to moist tissues could be prevented in detachment surgery and treatment of corneal herpes simplex if a micro-thin layer of a liquid with a very low freezing point intervened between the cryoprobe and the frozen tissue. Heat transmission would continue; however, adhesion would not occur. Following this idea, experiments utilizing a large series of substances with very low freezing points were tried, including glycerol, ethylene glycol, and alcohol (all antifreezes). At the

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