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September 1968


Arch Ophthalmol. 1968;80(3):415. doi:10.1001/archopht.1968.00980050417028

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In the June 1968 issue of the Archives Dr. Pinnas reported a case of possible association between macular lesions and the administration of allopurinol in the Registry of Interesting Cases (79:786-787 [June]).

In January 1965, a patient of mine who was also receiving allopurinol therapy for gout had a sudden decrease in vision from 20/20 to 20/40 due to small exudative lesions at the macula without any hemorrhages. Three months after discontinuation of allopurinol therapy, the patient's vision returned to 20/20, and this vision has been maintained constantly up to this time.

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