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October 1968

Toxemia of PregnancyAn Angiographic Interpretation of Fundus Changes

Author Affiliations

From Wills Eye Hospital, Philadelphia.

Arch Ophthalmol. 1968;80(4):449-454. doi:10.1001/archopht.1968.00980050451008

An unusual case of toxemia of pregnancy with bilateral, multiple, cyst-like elevations of the posterior pole unassociated with marked signs of retinal angiospasm is reported. Fluorescein angiography demonstrated abnormal choroidal leakage and pooling of dye into subretinal layers with minimal localized arteriolar constriction. These findings provide clinical evidence that the likely pathogenesis of detachments in toxemia of pregnancy is choroidal in origin.