An unusual case of toxemia of pregnancy with bilateral, multiple, cyst-like elevations of the posterior pole unassociated with marked signs of retinal angiospasm is reported. Fluorescein angiography demonstrated abnormal choroidal leakage and pooling of dye into subretinal layers with minimal localized arteriolar constriction. These findings provide clinical evidence that the likely pathogenesis of detachments in toxemia of pregnancy is choroidal in origin.
Gitter KA, Houser BP, Sarin LK, Justice J. Toxemia of PregnancyAn Angiographic Interpretation of Fundus Changes. Arch Ophthalmol. 1968;80(4):449-454. doi:10.1001/archopht.1968.00980050451008