A study of the effect of cycloplegia-mydriasis on the parameters of latent ocular nystagmus is reported. Cyclopentolate 1% (Cyclogyl) appears to decrease the amplitude, velocity, and, to a lesser extent, frequency of latent ocular nystagmus in a majority of the cases studied. This was associated with improvement in the monocularly recorded visual acuity. The interaction of latent nystagmus with manifest nystagmus, gaze nystagmus, and opticokinetic nystagmus, and their modification by cycloplegia indicated that separate neurologic centers are operative, and one may dominate another under different conditions. Possible explanations of the effect of the drug on nystagmus are discussed in relation to current theories of the etiology of latent nystagmus.
Windsor CE, Burian HM, Milojevic B. Modification of Latent NystagmusPart I. Arch Ophthalmol. 1968;80(5):657-663. doi:10.1001/archopht.1968.00980050659014