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December 1968

The Use of Adhesive for the Closure of Corneal PerforationsReport of Two Cases

Author Affiliations

From the Cornea Service, Massachusetts Eye and Ear Infirmary, the Department of Corneal Research, Institute of Biological and Medical Sciences, Retina Foundation, and the Cornea Service, Boston City Hospital, Boston.

Arch Ophthalmol. 1968;80(6):705-709. doi:10.1001/archopht.1968.00980050707004

The surgical adhesive n-heptyl 2-cyanoacrylate was used successfully to seal corneal perforations in two patients. There was prompt and permanent restoration of the anterior chamber, with minimal inflammatory response to the adhesive. The procedure of application was simple, performed at the slit lamp, and required only topical anesthesia. The adhesive acted as a tamponade allowing the normal healing process to occur beneath it, and eliminated the complications of suturing in diseased tissue. The encouraging results in these two cases may herald an even broader use of adhesives in ocular surgery.