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MULTIPLE SCLEROSIS AND VISION
Exacerbation of neurologic symptoms on exertion or overheating is frequently observed by patients with multiple sclerosis. In some, it may constitute the presenting complaint. The transient worsening of vision with retrobulbar neuritis of demyelinative origin is called Uhthoff's sign and has previously been editorialized in the Archives (Rucker, C. W.: Uhthoff's Symptom, 72: 141 [July] 1964). The following personal account by an anonymous patient with multiple sclerosis documents this symptom impressively.—D.G.C.It was my junior year in college when I had my first contact with a disease that was later to be identified as multiple sclerosis. I began to experience tingling in my right thigh. Its persistence made me nervous, but I tried to believe I had received an injury or a chill. In any case, I was too busy with part-time work and with my studies to consult a physician. But the strange sensation soon
News and Comment. Arch Ophthalmol. 1968;80(6):812. doi:10.1001/archopht.1968.00980050814025