Medrysone is a nonadrenal steroid closely related to progesterone. It has anti-inflammatory characteristics but does not increase the intraocular pressure. It does not apparently cause the reactivation of herpetic ulcers although its use in the sequelae of herpetic ulcers requires further evaluation. It has been used in a variety of conditions in 61 patients for 64 separate disease entities and appears to be a valuable addition to ocular therapeutics.
Bedrossian RH, Eriksen SP. The Treatment of Ocular Inflammation With Medrysone. Arch Ophthalmol. 1969;81(2):184-191. doi:10.1001/archopht.1969.00990010186008