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Article
February 1969

Temporal Aspects of the Electroretinogram

Author Affiliations

Bethesda, Md
From the Ophthalmology Branch, National Institute of Neurological Diseases and Blindness, National Institutes of Health, Public Health Service, Dept of Health, Education, and Welfare, Bethesda, Md. Dr. Berson's present address is Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, and the Children's Hospital Medical Center, 300 Longwood Ave, Boston.

Arch Ophthalmol. 1969;81(2):207-214. doi:10.1001/archopht.1969.00990010209011
Abstract

Changes in the electroretinogram (ERG) are studied in patients with large chorioretinal scars and certain hereditary retinal diseases. Amplitude and implicit time of the ERG responses are shown to behave independently of one another in these conditions. Chorioretinal destruction produces a reduction in amplitude but no change in implicit time. Hereditary disease leads to reduction in amplitude which can be accompanied by changes in implicit time. Some degenerations produce changes in implicit time before changes in amplitude. The delays in implicit time can be best explained by an abnormality of the rod and/or cone receptor system involving the entire retina. Alterations of implicit time due to the intensity and area of light stimulation and the state of retinal adaptation are considered.

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