The effect of cycloplegia on intraocular pressure was studied in a series of angle-closure glaucoma patients who had undergone peripheral iridectomies. Twenty percent of these patients had intraocular pressure elevations of at least 6 mm Hg though the angles remained unequivocally open. Analysis of the responsive group revealed that positive provocative tests were confined to those patients who had elevated intraocular pressures despite patent iridectomies. No positive responses occurred in postiridectomy normotensive eyes. The findings suggest that the same mechanism underlies cycloplegic responsiveness in this group as in patients with chronic simple glaucoma.
Harris LS, Galin MA. Cycloplegic Provocative Testing. Arch Ophthalmol. 1969;81(3):356-358. doi:10.1001/archopht.1969.00990010358010