[Skip to Content]
[Skip to Content Landing]
May 1969

Ultrastructure of Xanthelasma

Author Affiliations

San Francisco
From the Francis I. Proctor Foundation for Research in Ophthalmology and the Department of Ophthalmology, University of California Medical Center, San Francisco. Dr. Anderson is now at the Howe Laboratory of Ophthalmology, Boston.

Arch Ophthalmol. 1969;81(5):692-694. doi:10.1001/archopht.1969.00990010694015

Xanthelasma from both upper eyelids of a patient were examined by electron microscopy. The cytoplasm of the foam cells was filled with lipid droplets that were not bounded by a membrane. The lipid itself dissolved out during tissue preparation despite osmium or glutaraldehyde-osmium fixation, indicating that the lipid is highly unsaturated.