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June 1969

Fluorescein Angiography of Hereditary Retinal Degenerations

Author Affiliations

Bethesda, Md
From the Ophthalmology Branch, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Public Health Service, Dept of Health, Education, and Welfare, Bethesda, Md. Dr. Berson's present address is Department of Ophthalmology; Harvard Medical School and Massachusetts Eye and Ear Infirmary, and Children's Hospital Medical Center, 300 Longwood Ave, Boston. Dr. Geltzer's present address is Section of Ophthalmology, Yale University School of Medicine, New Haven, Conn.

Arch Ophthalmol. 1969;81(6):776-782. doi:10.1001/archopht.1969.00990010778004

A selected group of patients with hereditary retinal degeneration have been studied by electroretinography and fluorescein fundus photography. At early stages of the diseases, receptor cell damage occurs prior to marked disturbance in choroidal or retinal circulation. In advanced degeneration the fluorescein pattern can be altered by pigment migration within the retina.