Human donor corneas, stored at 4C or cryopreserved, were subjected to in-vitro perfusion, pachometry, and endothelial permeability determinations. The endothelial barrier mechanism and metabolic pump mechanism of the corneal dehydration system were thereby assessed at various durations of storage. Estimates of normal human endothelial permeability to urea and sucrose are presented.
Hoefle FB. Human Corneal Donor MaterialIn-Vitro Studies. Arch Ophthalmol. 1969;82(3):361-367. doi:10.1001/archopht.1969.00990020363013