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October 1969

Temporal ArteritisI. Smooth Muscle Cell Involvement

Author Affiliations

From the Howe Laboratory of Ophthalmology, Harvard University Medical School, Massachusetts Eye and Ear Infirmary, Boston.

Arch Ophthalmol. 1969;82(4):446-453. doi:10.1001/archopht.1969.00990020448004

The ultrastructure of normal and diseased temporal arteries is studied. Degeneration of the smooth muscle cells in the media appeared to be the initial pathological change. Fragmentation of the elastic fibers and giant cell reaction may be secondary to the destructive changes.