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Article
October 1969

A Case Report of Bilateral Microphthalmos With Cysts

Author Affiliations

Toronto
From the Hospital for Sick Children and the Department of Ophthalmology, University of Toronto, Toronto.

Arch Ophthalmol. 1969;82(4):480-482. doi:10.1001/archopht.1969.00990020482010
Abstract

CYSTS have been reported in association with microphthalmos. They develop after formation of the primary optic vesicle when the eye is between 7 to 14 mm in diameter. In other words, the primitive eye has formed, but the fetal cleft has either not closed or has closed defectively. At the site of the defect, the retina is everted to form a lining of the cyst wall. Neuroectodermal tissue continues to proliferate into the lower part of the orbit to form a cyst communicating directly with the interior of the eye. The neuroectodermal elements lining the cyst are dysplastic and poorly differentiated. Usually proliferating glial and fibrous tissue are also present. The cysts vary greatly in size and may be unilateral or bilateral.

Report of a Case  The following case is presented because of its dramatic clinical appearance, and the combination of very small eyes with extremely large cysts.

History and 

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