A common pattern of resolution of Kayser-Fleischer rings which is induced by the administration of penicillamine (D-penicillamine) is described. The lateral and medial portions of the ring disappear first, leaving superior and inferior crescents. The anatomy of these observations is discussed.
Sussman W, Scheinberg IH. Disappearance of Kayser-Fleischer RingsEffects of Penicillamine. Arch Ophthalmol. 1969;82(6):738-741. doi:10.1001/archopht.1969.00990020730003