Retinoblastomas were misdiagnosed as primary ocular inflammations without suspicion of neoplasm in 6.6% of 618 cases and as disease other than ocular inflammation in 8.3%—a total, therefore, of 14.9% misdiagnosed. Misdiagnosis and subsequent delay in therapy appeared to result in a markedly increased mortality in those cases. Intraocular retinoblastomas must be considered in the differential diagnosis of ocular inflammations of childhood.
Stafford WR, Yanoff M, Parnell BL. Retinoblastomas Initially Misdiagnosed as Primary Ocular Inflammations. Arch Ophthalmol. 1969;82(6):771-773. doi:10.1001/archopht.1969.00990020763008