Using stereologic techniques, electron micrographs of perinatal and adult rabbit corneal stroma were measured to determine the percent cell volume in each. The measured values of 40% (± 8.2) and 10.6% (± 3.8) for the perinatal and adult, respectively, agree well with our previously estimated values of 50% and 12.5%. The figure for the adult corneal stroma is two to three times that reported by others and should provide a more precise base for evaluating measurements of electrolyte concentrations in the corneal stroma.
Kaye GI. Stereologic Measurement of Cell Volume Fraction of Rabbit Corneal Stroma. Arch Ophthalmol. 1969;82(6):792-794. doi:10.1001/archopht.1969.00990020784013