After removal of the corneal epithelium, a contact lens was attached to Bowman's membrane with cyanoacrylate adhesive in 80 patients. In most instances the procedure was well tolerated, resulting in a quiet eye. In many cases vision improved substantially. The most significant complication (in one fourth of the cases so far) was regrowth of epithelium under the lens with subsequent irritation, requiring removal of the lens. The artificial epithelium procedure has already found an established indication in certain cases of corneal edema. Also, keratoconus, herpetic keratitis, acute chemical burn, and normal cornea in aphakia may benefit.
Dohlman CH, Carroll JM, Richards J, Refojo MF. Further Experience With Glued-on Contact Lens (Artificial Epithelium). Arch Ophthalmol. 1970;83(1):10-20. doi:10.1001/archopht.1970.00990030012004