Twenty rabbits received large doses of orally administered fluoride for 3 to 5 months. Baseline and subsequent electroretinogram (ERG) and ophthalmoscopic examinations were done on each rabbit as well as on a group of control rabbits. Although bone concentrations of fluoride were compatible with chronic system fluorosis, there were no significant differences in the ERGs, fundi, or microscopic sections of the treated eyes as compared to the control eyes.
Bloome MA, Burian HM. Chronic Fluoride Ingestion in RabbitsAbsence of Ocular Effects. Arch Ophthalmol. 1970;83(3):354-356. doi:10.1001/archopht.1970.00990030354014