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April 1970

Pterygium Tissue Culture Histoimmunological Study

Author Affiliations

Albuquerque, NM
From the Lovelace Foundation for Medical Education and Research, Albuquerque, NM. Dr. Josef Levy is now at the Department of Laboratory Medicine, University of Cincinnati School of Medicine, Cincinnati.

Arch Ophthalmol. 1970;83(4):402-405. doi:10.1001/archopht.1970.00990030402003

The ability of pterygium tissue to grow when attached to glass or plastic surfaces has been studied. This growth was achieved in over 50% of the pathological tissues, compared to 5% of normal control tissues. At surgery, without microscopic identification, the pterygium was divided into a corneal and a conjunctival portion. Growth rates of these portions were determined by several methods. Conjunctival pterygium tissue grew faster in the early stages but more slowly in the later stages than the corneal portion. No relation of growth rate and the age of the patient was found. The methods used appeared to be accurate enough to evaluate the effects of various physical and chemical agents on pterygium tissue growth in vitro. No circulating antibodies to pterygium tissue were found in patients serum using the tanned cell hemagglutination technique.