A method of sealing choroidal perforations using isobutyl cyanoacrylate adhesive is described. The adhesive can be applied by itself using a polyethylene applicator, or it can be used to glue on a silicone patch depending on the size of the perforation. The glue has good strength and appears to be relatively nontoxic to the ocular tissues when used in small amounts. Possible uses of adhesive in retinal detachment surgery are proposed.
Seelenfreund MH, Refojo MF, Schepens CL. Sealing Choroidal Perforations With Cyanoacrylate Adhesives. Arch Ophthalmol. 1970;83(5):619-625. doi:10.1001/archopht.1970.00990030619018