Photocoagulation applied to the retinoschisis cavity in five eyes with congenital retinoschisis not only failed to ameliorate the disease but caused holes in the external layer, or both layers, and subsequent retinal detachment. Until more is learned about the pathogenesis and course of congenital retinoschisis, it is recommended that photocoagulation treatment of the external layer not be performed. Photocoagulation applied in intact retina just posterior to the advancing edge of the congenital retinoschisis in two eyes did not aggravate the disease. Moreover, the retinoschisis has been stationary for three years in each patient.
Brockhurst RJ. Photocoagulation in Congenital Retinoschisis. Arch Ophthalmol. 1970;84(2):158-165. doi:10.1001/archopht.1970.00990040160007