Eleven patients with Behçet's (and neuro-Behçet's) disease in the active and progressive stages were treated with chlorambucil (Leukeran). Follow-up varied between three weeks and 17 months. Results were favorable in all, and the drug was superior to other forms of treatment in that there was arrest and some amelioration of the disease.
Mamo JG, Azzam SA. Treatment of Behçet's Disease With Chlorambucil. Arch Ophthalmol. 1970;84(4):446-450. doi:10.1001/archopht.1970.00990040448008