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November 1970

Choroidal Neovascularization in Multifocal (Presumed Histoplasmin) Choroiditis

Author Affiliations

From the Eye Research Laboratories, University of Chicago, Chicago.

Arch Ophthalmol. 1970;84(5):595-604. doi:10.1001/archopht.1970.00990040597007

Fifteen patients with multifocal choroiditis and greenish discoloration associated with typical macular lesions were studied by rapid sequence fluorescein angiography. In all cases new vessels could be identified at these sites during fluorescein angiography, particularly during the late arterial and early retinal venous phases. Chronic serous fluid formation frequently results in new vessel proliferation, and this in turn alters the overlying pigment epithelium, causing a greenishgray appearance on ophthalmoscopic evaluation. Photocoagulation is a logical form of treatment once new vessels can be identified, particularly if hemorrhage has occurred.