A family has three siblings suffering from congenital corneal dystrophy in association with progressive sensorineural deafness. With the parents of the propositi being first cousins, an autosomal recessive mode of inheritance is suggested. All the positive findings in these patients are attributed to a single gene.
Harboyan G, Mamo J, Kaloustian VD, Karam F. Congenital Corneal DystrophyProgressive Sensorineural Deafness in a Family. Arch Ophthalmol. 1971;85(1):27-32. doi:10.1001/archopht.1971.00990050029005