This study presents nine cases of confirmed metastatic endophthalmitis. Seven patients underwent immunologic evaluation. All patients were treated with locally and systemically administered antibiotics; six patients received local corticosteroid in addition to the antibiotic. Four patients died during hospitalization. Of the seven eyes (five patients) treated with combined corticosteroid therapy, all showed improvement, two attained a visual acuity of >20/200, and four achieved a visual acuity of >20/40. Immunologic evaluation revealed some abnormality in all seven patients tested. This finding is discussed as it affects the relationship of host response and infectious agent to the disease process.
Aronson SB, Sussman SJ, Moore TE, Williams FC, Goodner EK. Corticosteroid Therapy in Metastatic Endophthalmitis. Arch Ophthalmol. 1971;85(1):61-70. doi:10.1001/archopht.1971.00990050063009