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February 1971


Author Affiliations

Rochester, Minn

Arch Ophthalmol. 1971;85(2):256. doi:10.1001/archopht.1971.00990050258027

To the Editor.  —Recent articles have discussed pathologic conditions in which cartilage is found within the eye. The relationship of intraocular cartilage to diktyoma has been remarked upon by several authors.1,2 Cogan and Kuwabara3 noted its occurrence in microphthalmic eyes in 13-15 trisomy. Zimmerman and Font4 emphasized that in this condition the cartilage is related to a coloboma of the ciliary body or iris and arises in the cornea or sclera, becoming continuous with an intraocular mass of persistent hyperplastic primary vitreous. Manschot5 stated that intraocular cartilage may be found with persistent hyperplastic primary vitreous, as well as in a microphthalmic eye from a cyclopic orbit.2 Recently, Yanoff and Font2 reported finding cartilage and persistent hyperplastic primary vitreous in a microphthalmic eye from a chromosomally normal child; in contradistinction to 13-15 trisomy, the cartilage occurred within a mass of connective tissue in the center

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