A method of predicting the location of retinal holes has been formulated. It is based on the fact that the development of subretinal fluid, following the occurrence of a retinal tear, is governed by a limited number of anatomical factors and gravity. As a result, detachments form in a predictable manner around the tear or hole of their origin, and the shape of the detachment points to the position of the retinal hole. One thousand retinal detachments were analyzed, and they confirm this concept.
Lincoff H, Gieser R. Finding the Retinal Hole. Arch Ophthalmol. 1971;85(5):565-569. doi:10.1001/archopht.1971.00990050567007