A fluorophotometric technique for simultaneous measurement of fluorescein arrival upon the rabbit fundus shows that differentiation between occluded and normal carotid artery circulation is possible. In addition, it is possible to use such a device in the study of normal and abnormal human retinal circulation.
Lavenstein B, Milder B, Winkelman JZ, Zappia RJ, Gay AJ. Retinal and Choroidal Circulation in RabbitsFluorophotometer Measurements in Animals With and Without Carotid Artery Occlusion. Arch Ophthalmol. 1971;85(6):723-729. doi:10.1001/archopht.1971.00990050725014