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July 1971

Cycloplegic Provocative Testing After Topical Administration of Steroids

Author Affiliations

New York
From the Department of Ophthalmology, New York Medical College, New York.

Arch Ophthalmol. 1971;86(1):12-14. doi:10.1001/archopht.1971.01000010014003

Elevation of intraocular pressure after the topical application of cyloplegic, though rarely noted in the normal population, is seen in some 25% of the open angle glaucomatous population. No positive cycloplegic provocative responses were elicited from a population of 58 normals. After three weeks of treatment with topically administered dexamethasone, however, a 19% incidence of positive cycloplegic provocative tests was found in this same group. No correlation was noted between poststeroid intraocular pressure and cyloplegic-induced pressure elevation, but a statistically significant, inverse correlation between positive cycloplegic responses and outflow facility was noted after steroid treatment. The phenomenon of cycloplegic-induced pressure elevation thus appears to be related more closely to impaired outflow facility than to pretesting intraocular pressure levels.