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July 1971

The Fixed Dilated PupilSudden Iridoplegia or Mydriatic Drops? A Simple Diagnostic Test

Author Affiliations

Iowa City; Bethesda, Md; New York
From the Department of Ophthalmology, University of Iowa, Iowa City (Dr. Thompson); the National Eye Institute, Bethesda, Md (Dr. Newsome); and the Lowenstein Laboratory of Pupillography, Presbyterian Hospital, and Department of Ophthalmology, Columbia University, College of Physicians and Surgeons, New York (Dr. Loewenfeld).

Arch Ophthalmol. 1971;86(1):21-27. doi:10.1001/archopht.1971.01000010023006

Isolated iridoplegia or internal ophthalmoplegia may be due to impairment of the effector muscles in the eye, defective parasympathetic innervation, or the presence of atropinic substances in the eye. Pharmacologic blockade can be identified by the pupil's failure to constrict to pilocarpine drops. Because of its clarity and technical simplicity, this test should be in general use as an office procedure.