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August 1971

Light Coagulation in Presumed Histoplasmic ChoroiditisA Controlled Clinical Study

Author Affiliations

Iowa City
From the departments of ophthalmology (Dr. Watzke), and preventive medicine and environmental health (Dr. Leaverton), University of Iowa College of Medicine, Iowa City.

Arch Ophthalmol. 1971;86(2):127-132. doi:10.1001/archopht.1971.01000010129002

A controlled study was designed to evaluate light coagulation as treatment for presumed histoplasmic chorioretinitis. Twenty-nine patients were selected. Allocation of patients to a treatment or an untreated control group was made by using a table of random numbers. Results in the two groups were compared over a one-year observation period. The study was designed to minimize measurement and observation bias and the effect of interim remissions and exacerbations of the disease. The results indicate that this therapy is of no value in the long-term management of this disease.