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Article
August 1971

FluorometholoneAnti-inflammatory and Intraocular Pressure Effects

Author Affiliations

Irvine, Calif; Stanford, Calif
From Allergan Pharmaceuticals, Irvine, Calif (Mr. Fairbairn), and the Department of Ophthalmology, Stanford University School of Medicine, Stanford, Calif.

Arch Ophthalmol. 1971;86(2):138-141. doi:10.1001/archopht.1971.01000010140004
Abstract

Fluorometholone 0.1% ophthalmic suspension applied topically was found to be an effective treatment in 308 patients with mild to severe noninfectious inflammatory disorders of the eye. The effect of fluorometholone on intraocular pressure was examined in steroid reactors who had accurately documented histories of pressure responses to prednisolone, dexamethasone, or betamethasone. The drug was also tested in a relatively large random patient population, including many with glaucoma, whose intraocular pressures were observed. The results of these studies indicate that fluorometholone shows a substantially reduced tendency to increase intraocular pressure as compared to several other steroids used topically.

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