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August 1971

Opsoclonus as the Initial Manifestation of Occult Neuroblastoma

Author Affiliations

Rochester, Minn
From the Department of Neurology, Mayo Clinic and Mayo Foundation (Dr. Sandok), and the Mayo Graduate School of Medicine (University of Minnesota) (Dr. Kranz), Rochester, Minn.

Arch Ophthalmol. 1971;86(2):235-236. doi:10.1001/archopht.1971.01000010237018

Opsoclonus was the initial manifestation of an associated neuroblastoma. Although symptomatic control of the ocular symptoms can be achieved by the use of corticotropin (ACTH), it is important to recognize that this unusual ocular symptom may be a manifestation of an occult, but potentially treatable malignant neoplasm and to undertake appropriate diagnostic studies which might uncover its existence.