A patient was affected with keratitis associated with unequivocal Reiter's disease. After a two-week prodrome of nonfollicular conjunctivitis, numerous central epithelial and subepithelial opacities appeared OU. Later, ragged epithelial erosions developed and healed spontaneously. The epithelial and subepithelial opacities faded and were replaced by foci of central punctate stromal keratitis which disappeared within a month. Subsequently, new marginal subepithelial opacities appeared, faded, and were replaced by marginal punctate stromal keratitis. Two months after onset, both corneas were completely clear. Smears and cultures for Chlamydia, adenovirus, herpesvirus, and bacteria were negative. Microimmunofluorescent screening of one acute and two convalescent sera against ten chlamydia, antigens were negative. It is concluded that Reiter's keratitis represents a nosologic entity of clinical usefulness by virtue of its distinctive features.
Mills RP, Kalina RE. Reiter's Keratitis. Arch Ophthalmol. 1972;87(4):447-449. doi:10.1001/archopht.1972.01000020449017