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Article
August 1972

Pathology of Hereditary Juvenile Retinoschisis

Author Affiliations

Rotterdam, Netherlands
From the Ophthalmic Pathology Laboratory, Medical Faculty Rotterdam, Netherlands, and the Registry of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC.

Arch Ophthalmol. 1972;88(2):131-138. doi:10.1001/archopht.1972.01000030133002
Abstract

The clinicopathologic data are presented in one familial case and in two other cases of juvenile retinoschisis in which the family history was not available. The principal feature in all three cases is a large retinal schisis cavity, the anterior wall of which has become a retrolental membrane that is responsible for the clinical picture of leukokoria. The schisis is seen histologically as a splitting within the nerve fiber layer. It appears impossible to state whether the changes found in the pigment epithelium of the posterior pole are secondary to the changes in the sensory retina.

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