The clinical and histopathologic findings in a case of lipoid proteinosis are described. Electron micrographs demonstrated the presence of an extracellular, finely granular, amorphous material located in patchy distribution throughout the dermis and about blood vessels in the lids and lip. Collagen fibers were normal. It is suggested that the different character of these deposits as compared to those in previous reports might be the result of the biopsy of lesions at different stages of development.
Jensen AD, Khodadoust AA, Emery JM. Lipoid ProteinosisReport of a Case With Electron Microscopic Findings. Arch Ophthalmol. 1972;88(3):273-277. doi:10.1001/archopht.1972.01000030275011