[Skip to Content]
[Skip to Content Landing]
September 1972

Iris Wound Healing

Author Affiliations

Little Rock, Ark
From the departments of ophthalmology and pharmacology, University of Arkansas Medical Center, and the Veterans Administration Hospital, Little Rock, Ark.

Arch Ophthalmol. 1972;88(3):296-304. doi:10.1001/archopht.1972.01000030298015

A longitudinal iridotomy was made in the rabbit between the major iris arteries. The wound edges remained in apposition, and soon after injury epithelial cells of the iris migrated and elongated to cover the wound edge. One day after injury epithelial, endothelial, and stromal cells began to undergo cell division. During the next several months, the wound gradually healed as new cells and collagen fibrils filled the defect. This is the first demonstration that iris tissue has the potential to heal and scar formation does not occur.