The effect of aceclidine on human intraocular pressure was studied. A dose relationship to 0.5%, 1%, 2%, and 4% aceclidine was established. The 4% aceclidine had a similar pressure lowering response to 2% pilocarpine. The duration of the four concentrations of aceclidine on intraocular pressure lasted at least seven hours.
Drance SM, Schulzer M. Dose Response of Human Intraocular Pressure to Aceclidine. Arch Ophthalmol. 1972;88(4):394-396. doi:10.1001/archopht.1972.01000030396008