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December 1972

Congenital Anomalies in Duane's Retraction Syndrome

Author Affiliations

Rochester, Minn; Baltimore; Rochester, Minn
From the Department of Ophthalmology, Mayo Clinic and Mayo Foundation, Rochester, Minn (Drs. Pfaffenbach and Kearns), and the Wilmer Ophthalmological Institute, Johns Hopkins Hospital, Baltimore (Dr. Cross).

Arch Ophthalmol. 1972;88(6):635-639. doi:10.1001/archopht.1972.01000030637013

Patients with sporadic Duane's retraction syndrome (congenital aberrant innervation) appear to have a significant increase in the number of associated congenital malformations. These are primarily facial anomalies, ear and hearing anomalies, skeletal deformities, and roentgenographic malformations in the upper vertebral column and rib cage. The critical time in embryologic development resulting in these anomalies is the fourth to the eighth week of gestation.