Cell-free filtrates of cultures of Staphylococcus epidermidis were prepared from patients with definite clinical signs and symptoms of staphylococcic blepharoconjunctivitis. The subconjuctival injection of rabbit eyes with these filtrates was performed, and the results were compared with those produced in another group of rabbits similarly injected with filtrates of S aureus strains. Although less severe than the disease produced by the S aureus filtrates, a significant and sometimes severe toxicogenic conjunctivitis was produced by the S epidermidis filtrates.
Valenton MJ, Okumoto M. Toxin-Producing Strains of Staphylococcus epidermidis (albus)Isolates From Patients With Staphylococcic Blepharoconjunctivitis. Arch Ophthalmol. 1973;89(3):186-189. doi:10.1001/archopht.1973.01000040188004