Labrador keratopathy and Bietti's nodular dystrophy are acquired corneal degenerations affecting men who have spent their working lives outdoors; they are thought to be caused by climatic exposure. This report shows that such corneal disease occurs more frequently than has been suspected and suggests ultraviolet irradiation as a common etiogenic factor. Since the clinical appearances and pathologic changes in all cases are similar, differing only in degree of severity, it is suggested that these diseases be considered a single entity called climatic droplet keratopathy.
Freedman A. Climatic Droplet KeratopathyI. Clinical Aspects. Arch Ophthalmol. 1973;89(3):193-197. doi:10.1001/archopht.1973.01000040195006