Optic-disc Pallor was evaluated in 280 eyes of 140 normal subjects distributed evenly by sex and age over seven decades. From colored photographs of the disc 15×-enlarged black and white prints of high contrast were made. Relative measurements were determined from the prints. Median or 50th percentile value for area pallor/area disc was 19%; 95th percentile value was 38%. With age, pallor area relative to disc increases about 50% and enlarges more nasally than temporally. Comparison of sex and race showed that white males have larger relative areas of pallor than white females. With this technique, degree of optic-disc pallor can be evaluated quantitatively and used for further defining changes of the optic disc in glaucoma and for screening purposes.
Schwartz B, Reinstein NM, Lieberman DM. Pallor of the Optic DiscQuantitative Photographic Evaluation. Arch Ophthalmol. 1973;89(4):278-286. doi:10.1001/archopht.1973.01000040280003