September 1973

Thioridazine Pigmentary Retinopathy

Author Affiliations

Columbus, Ohio
From the Department of Ophthalmology, Ohio State University, Columbus.

Arch Ophthalmol. 1973;90(3):251-255. doi:10.1001/archopht.1973.01000050253014

A case of thioridazine pigmentary retinopathy was followed-up for a six-year period. The initial insult to the choriocapillaris, pigment epithelium, and photoreceptors caused a progressive alteration in not only the ophthalmoscopic appearance but also the visual function. There was a progressive visual field loss as well as an alteration in the macular electroretinogram. I emphasize the progressive nature of this condition even after the drug has been discontinued. Periodic follow-up examinations are advised.