A healthy 18-year-old boy with a past history of repeated episodes of dendritic keratitis in the left eye developed a rapidly growing, lightly pigmented iris tumor in the same eye. Malignant melanoma was suspected and an excisional biopsy was performed. Histopathologic examination of the tumor revealed a focal iris abscess. The cause of the abscess was not determined. Electron microscopic examination of the tumor failed to identify viral particles.
Focal iris abscess must be included in the differential diagnosis of malignant melanoma of the iris.
Gass JDM. Iris Abscess Simulating Malignant Melanoma. Arch Ophthalmol. 1973;90(4):300-302. doi:10.1001/archopht.1973.01000050302011