[Skip to Content]
[Skip to Content Landing]
Article
November 1973

Ocular Fundus in Acute Leber Optic Neuropathy

Author Affiliations

Miami, Fla; San Francisco; Miami, Fla
From the Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Fla (Drs. Smith and Susac), and the Neuro-ophthalmology Unit, departments of ophthalmology, neurosurgery, and neurology, University of California School of Medicine, San Francisco (Dr. Hoyt).

Arch Ophthalmol. 1973;90(5):349-354. doi:10.1001/archopht.1973.01000050351002
Abstract

In the acute phase of Leber optic neuropathy, there are three characteristic fundus changes: (1) circumpapillary telangiectatic microangiopathy, (2) swelling of the nerve fiber layer around the disc ("pseudoedema"), and (3) absence of staining on fluorescein angiography. These findings are illustrated by eight cases and in our experience are pathognomonic for this disease.

×