A patient had a mass associated with a pterygium in the same eye. Microscopic diagnosis of the original lesion was granuloma pyogenicum.
Routine excision, excision with cautery, thiotepa therapy and beta irradiation, excision with nonreactive suture material, and topically applied steroids all failed to prevent its recurrence. The pathologic findings of each recurrence remained basically the same as in the original lesion.
Boockvar W, Wessely Z, Ballen P. Recurrent Granuloma Pyogenicum of Limbus. Arch Ophthalmol. 1974;91(1):42-44. doi:10.1001/archopht.1974.03900060046011