A strictly enforced management plan of bed rest, sedation, binocular eye pads, and immediate treatment with orally administered prednisone was used on 50 consecutive patients with traumatic hyphema who were treated in the years 1967 to 1972. No instance of secondary hemorrhage was encountered.
This series was compared with the previous 50 cases of traumatic hyphema that were treated in a variety of ways, but did not include the use of systemically administered prednisone. An 18% incidence of secondary hemorrhage occurred. The composition of the two groups was similar.
On the basis of this study, it may be concluded that the immediate use of orally administered prednisone in traumatic hyphema reduces markedly the incidence of secondary hemorrhage.
Yasuna E. Management of Traumatic Hyphema. Arch Ophthalmol. 1974;91(3):190-191. doi:10.1001/archopht.1974.03900060198008